Breast cancer (mammary carcinoma) treatment options
& modern immunotherapies
Breast cancer is the most common cancer among women. Thanks to modern diagnostics, personalized therapies, and increasingly immunological approaches, more treatment options are available today than ever before.
The choice of therapy always depends on the type of tumor, its stage, genetics, and the patient's general condition.
Classic treatment methods
1. Operation (breast-conserving or mastectomy)
In early stages, surgery is often the first step. The goal is to remove the tumor completely.
2. Radiation therapy
It is often used after breast-conserving surgery. It reduces the risk of local recurrence.
Note: Not all patients require radiation therapy – certain molecular tumor profiles now allow for adapted strategies.
3. Chemotherapy
It acts systemically throughout the body. It is frequently used for aggressive or hormone receptor-negative tumors.
4. Antihormone therapy (endocrine therapy)
Effective in hormone receptor-positive tumors (ER/PR-positive).
This includes:Tamoxifen
Aromatase inhibitors
Ovarian suppression
CDK4/6 inhibitors (e.g. abemaciclib)
5. Antibody and targeted therapies
For HER2-positive tumors, modern antibodies and antibody-drug conjugates are used. Personalized drug options are available for genetic alterations such as ESR1, PIK3CA, and BRCA.
Modern immunotherapies for breast cancer
Immunotherapies aim to strengthen the immune system and specifically recognize and fight cancer cells. Immunological approaches include:
Dendritic cell therapy (DCT)
Dendritic cell therapy utilizes the patient's own immune system.
This will include:
Blood cells taken
cultured into dendritic cells in a GMP laboratory
loaded with tumor antigens
matured into highly active immune cells
injected back into the skin
Goal: Activation of T cells that can specifically recognize and attack tumor cells.
The DZT is produced individually for each patient and can be used for various types of breast cancer – regardless of whether the tumor is hormone-positive, HER2-negative or triple-negative.
Combination therapies – why they can be beneficial
In modern oncology, there is an increasing trend towards combining methods to utilize multiple biological mechanisms simultaneously.
Possible combinations to support the immune system:
DZT + Immune boost
e.g.
Glutathion
Artesunate
Resveratrol
selenium
These substances can help reduce oxidative stress and stabilize immune function.
DZT + endocrine therapy
In ER-positive breast cancer (e.g., Luminal A/B).
The DZT can complement the tumor-directed immune response here.
DZT + targeted therapies
In cases of mutations such as PIK3CA or ESR1, classical therapies can be combined with immunological strategies.
DZT + local procedures
e.g. cryoablation or ozone therapy as part of complementary approaches.
The goal of immunotherapy in breast cancer
to activate the immune system
To make tumor cells more easily recognizable
to reduce tumor burden
to stabilize the quality of life
to slow the progression of the disease
Important: Every patient reacts individually; immunotherapies do not replace guideline-based treatment.
Dendritic cell therapy is a patient-specific immunological approach.
No promises of healing are made.